diagnostic criteria for pediatric mitochondrial disorders

Current molecular diagnostic algorithm for mitochondrial disorders.

Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due in part to the biochemical complexity of mitochondrial respiration and the fact that two genomes, one mitochondrial and one nuclear, encode the components of the respiratory chain. Because of the large number of genes involved, attempts to classify mitochondrial RCD incorporate ...

Lucid Flowchart of the Diagnostic Criteria for Temporomandibular Joint Disorders

‘Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders (DC/TMD)’ and ‘Diagnostic criteria for temporomandibular disorders (DC/TMD) for clinical and research applications: recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group’ have provided a comprehensive guidance for the TMD taxonomy. However, a flowchart that is q...

Diagnostic criteria for work-related upper limb disorders.

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG). Prior NMO diagnostic criteria required optic nerve and spinal cord involvement but more restricted or more extensive CNS involvement may occur. The International Panel for NMO Diagnosis (IPND) was convened to develop r...

Mitochondrial disorders: Overview of diagnostic tools and new diagnostic trends

Mitochondrial disorders typically present with widespread, clinical features in all age groups and ethnicities and are often progressive and degenerative in nature. Because their clinical presentation is so variable and typically leads to widespread multisystem problems, diagnosis based on history and physical findings alone is often difficult, particularly for physicians unfamiliar with this g...

The hypnotic diagnostic interview for hysterical disorders, pediatric form.

This article reports on the use of hypnosis to facilitate the diagnostic process in two cases of pediatric hysterical reactions. The Hypnotic Diagnostic Interview for Hysterical Disorders (HDIHD), an interview tool, specifically designed for these cases, is reported. The first case was an adolescent male with motor Conversion Disorder manifested as paralysis of his lower limbs. The second was a...